Cargando…

Probing the evolutionary robustness of two repurposed drugs targeting iron uptake in Pseudomonas aeruginosa

LAY SUMMARY: We probed the evolutionary robustness of two antivirulence drugs, gallium and flucytosine, targeting the iron-scavenging pyoverdine in the opportunistic pathogen Pseudomonas aeruginosa. Using an experimental evolution approach in human serum, we showed that antivirulence treatments are...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rezzoagli, Chiara, Wilson, David, Weigert, Michael, Wyder, Stefan, Kümmerli, Rolf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234326/ https://www.ncbi.nlm.nih.gov/pubmed/30455950 http://dx.doi.org/10.1093/emph/eoy026

Ejemplares similares

Combining antibiotics with antivirulence compounds can have synergistic effects and reverse selection for antibiotic resistance in Pseudomonas aeruginosa
por: Rezzoagli, Chiara, et al.
Publicado: (2020)

Siderophore cheating and cheating resistance shape competition for iron in soil and freshwater Pseudomonas communities
por: Butaitė, Elena, et al.
Publicado: (2017)

The path to re-evolve cooperation is constrained in Pseudomonas aeruginosa
por: Granato, Elisa T., et al.
Publicado: (2017)

Coordination of siderophore gene expression among clonal cells of the bacterium Pseudomonas aeruginosa
por: Mridha, Subham, et al.
Publicado: (2022)

Enforced specialization fosters mutual cheating and not division of labour in the bacterium Pseudomonas aeruginosa
por: Mridha, Subham, et al.
Publicado: (2022)

Ecology drives the evolution of diverse social strategies in Pseudomonas aeruginosa
por: Figueiredo, Alexandre R. T., et al.
Publicado: (2021)

Single-Cell Imaging Reveals That Staphylococcus aureus Is Highly Competitive Against Pseudomonas aeruginosa on Surfaces
por: Niggli, Selina, et al.
Publicado: (2021)

Gallium-mediated siderophore quenching as an evolutionarily robust antibacterial treatment
por: Ross-Gillespie, Adin, et al.
Publicado: (2014)

Evolution of Quorum Sensing in Pseudomonas aeruginosa Can Occur via Loss of Function and Regulon Modulation
por: Jayakumar, Priyanikha, et al.
Publicado: (2022)

Rapid and strain-specific resistance evolution of Staphylococcus aureus against inhibitory molecules secreted by Pseudomonas aeruginosa
por: Niggli, Selina, et al.
Publicado: (2023)

Repurposing Anti-diabetic Drugs to Cripple Quorum Sensing in Pseudomonas aeruginosa
por: Hegazy, Wael A. H., et al.
Publicado: (2020)

Cell aggregation promotes pyoverdine-dependent iron uptake and virulence in Pseudomonas aeruginosa
por: Visaggio, Daniela, et al.
Publicado: (2015)

Pseudomonas aeruginosa adapts its iron uptake strategies in function of the type of infections
por: Cornelis, Pierre, et al.
Publicado: (2013)

Do Bacterial “Virulence Factors” Always Increase Virulence? A Meta-Analysis of Pyoverdine Production in Pseudomonas aeruginosa As a Test Case
por: Granato, Elisa T., et al.
Publicado: (2016)

Repurposing metformin as a quorum sensing inhibitor in Pseudomonas aeruginosa
por: Abbas, Hisham A, et al.
Publicado: (2017)

Biofilm-specific uptake of a 4-pyridone-based iron chelator by Pseudomonas aeruginosa
por: Houshmandyar, Sharareh, et al.
Publicado: (2021)

A Test of Evolutionary Policing Theory with Data from Human Societies
por: Kümmerli, Rolf
Publicado: (2011)

Iron acquisition strategies in pseudomonads: mechanisms, ecology, and evolution
por: Kümmerli, Rolf
Publicado: (2022)

Repurposing of Drugs for Antibacterial Activities on Selected ESKAPE Bacteria Staphylococcus aureus and Pseudomonas aeruginosa
por: Kamurai, Bridget, et al.
Publicado: (2020)

The Genomic Basis of Evolutionary Innovation in Pseudomonas aeruginosa
por: Toll-Riera, Macarena, et al.
Publicado: (2016)

Repurposing the anticancer drug cisplatin with the aim of developing novel Pseudomonas aeruginosa infection control agents
por: Yuan, Mingjun, et al.
Publicado: (2018)

Evolutionary diversification of Pseudomonas aeruginosa in an artificial sputum model
por: Davies, Emily V., et al.
Publicado: (2017)

Synergistic Activity of Repurposed Peptide Drug Glatiramer Acetate with Tobramycin against Cystic Fibrosis Pseudomonas aeruginosa
por: Murphy, Ronan A., et al.
Publicado: (2022)

Repurposing Dimetridazole and Ribavirin to disarm Pseudomonas aeruginosa virulence by targeting the quorum sensing system
por: Yuan, Yang, et al.
Publicado: (2022)

Regulation of Pseudomonas aeruginosa Virulence by Distinct Iron Sources
por: Reinhart, Alexandria A., et al.
Publicado: (2016)

Evolutionary conservation of essential and highly expressed genes in Pseudomonas aeruginosa
por: Dötsch, Andreas, et al.
Publicado: (2010)

Strategies for Zinc Uptake in Pseudomonas aeruginosa at the Host–Pathogen Interface
por: Wang, Shuaitao, et al.
Publicado: (2021)

Repurposing the Native Type I-F CRISPR-Cas System in Pseudomonas aeruginosa for Genome Editing
por: Xu, Zeling, et al.
Publicado: (2020)

Rapid identification of pyoverdines of fluorescent Pseudomonas spp. by UHPLC-IM-MS
por: Rehm, Karoline, et al.
Publicado: (2022)

Biosynthesis of iron oxide magnetic nanoparticles using clinically isolated Pseudomonas aeruginosa
por: Khan, Abid Ali, et al.
Publicado: (2021)

TonB-Dependent Receptor Repertoire of Pseudomonas aeruginosa for Uptake of Siderophore-Drug Conjugates
por: Luscher, Alexandre, et al.
Publicado: (2018)

Efficacy of Artesunate against Pseudomonas aeruginosa Biofilm Mediated by Iron
por: Bao, Lei, et al.
Publicado: (2019)

Convergent Metabolic Specialization through Distinct Evolutionary Paths in Pseudomonas aeruginosa
por: La Rosa, Ruggero, et al.
Publicado: (2018)

Evolutionary stability of collateral sensitivity to antibiotics in the model pathogen Pseudomonas aeruginosa
por: Barbosa, Camilo, et al.
Publicado: (2019)

The Transcriptional Regulator Np20 Is the Zinc Uptake Regulator in Pseudomonas aeruginosa
por: Ellison, Matthew L., et al.
Publicado: (2013)

Probing the internal micromechanical properties of Pseudomonas aeruginosa biofilms by Brillouin imaging
por: Karampatzakis, A., et al.
Publicado: (2017)

Colorimetric bacteria sensing of Pseudomonas aeruginosa using gold nanoparticle probes
por: Mousivand, Zahra, et al.
Publicado: (2023)

Biomimetic enterobactin analogue mediates iron-uptake and cargo transport into E. coli and P. aeruginosa
por: Zscherp, Robert, et al.
Publicado: (2021)

Quorum sensing triggers the stochastic escape of individual cells from Pseudomonas putida biofilms
por: Cárcamo-Oyarce, Gerardo, et al.
Publicado: (2015)

A comprehensive method to elucidate pyoverdines produced by fluorescent Pseudomonas spp. by UHPLC-HR-MS/MS
por: Rehm, Karoline, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_japrsgstnpa6taljksu6oq2jjt