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Spermidine/spermine N1-acetyltransferase-1 as a diagnostic biomarker in human cancer

AIM: SSAT-1 is an enzyme that plays a critical role in cell growth. Amantadine, a FDA-approved antiviral drug, is a substrate for SSAT-1. The utility of amantadine as an agent to demonstrate elevated SSAT-1 activity linked to cancer was conducted. RESULTS: High levels of SSAT-1 expression were measu...

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Detalles Bibliográficos
Autores principales: Maksymiuk, Andrew W, Sitar, Daniel S, Ahmed, Rashid, Cheng, Brian, Bach, Horacio, Bagchi, Rushita Adhikari, Aroutiounova, Nina, Tappia, Paramjit S, Ramjiawan, Bram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234463/
https://www.ncbi.nlm.nih.gov/pubmed/30450232
http://dx.doi.org/10.4155/fsoa-2018-0077