Utility of Glycosylated TIMP3 molecules: Inhibition of MMPs and TACE to improve cardiac function in rat myocardial infarct model

Tissue Inhibitor of Metalloproteinase 3 (TIMP3) is a secreted protein that has a great utility to inhibit elevated metalloproteinase (MMP) activity in injured tissues including infarcted cardiac tissue, inflamed vessels, and joint cartilages. An imbalance between TIMP3 and active MMP levels in the l...

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Detalles Bibliográficos
Autores principales: Chintalgattu, Vishnu, Greenberg, Joanne, Singh, Shivani, Chiueh, Venice, Gilbert, Amy, O'Neill, Jason W., Smith, Stephen, Jackson, Simon, Khakoo, Aarif Y., Lee, TaeWeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234480/
https://www.ncbi.nlm.nih.gov/pubmed/30459952
http://dx.doi.org/10.1002/prp2.442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234480/
https://www.ncbi.nlm.nih.gov/pubmed/30459952
http://dx.doi.org/10.1002/prp2.442

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