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Utility of Glycosylated TIMP3 molecules: Inhibition of MMPs and TACE to improve cardiac function in rat myocardial infarct model
Tissue Inhibitor of Metalloproteinase 3 (TIMP3) is a secreted protein that has a great utility to inhibit elevated metalloproteinase (MMP) activity in injured tissues including infarcted cardiac tissue, inflamed vessels, and joint cartilages. An imbalance between TIMP3 and active MMP levels in the l...
Autores principales: | Chintalgattu, Vishnu, Greenberg, Joanne, Singh, Shivani, Chiueh, Venice, Gilbert, Amy, O'Neill, Jason W., Smith, Stephen, Jackson, Simon, Khakoo, Aarif Y., Lee, TaeWeon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234480/ https://www.ncbi.nlm.nih.gov/pubmed/30459952 http://dx.doi.org/10.1002/prp2.442 |
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