Discovery of a Small Molecule to Increase Cardiomyocytes and Protect the Heart After Ischemic Injury

Accumulating data suggest that new cardiomyocytes in adults are generated from existing cardiomyocytes throughout life. To enhance the endogenous cardiac regeneration, we performed chemical screenings to identify compounds that activate pro-proliferative YES-associated protein and transcriptional en...

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Detalles Bibliográficos
Autores principales: Hara, Hironori, Takeda, Norifumi, Kondo, Masaki, Kubota, Mio, Saito, Tatsuo, Maruyama, Junichi, Fujiwara, Takayuki, Maemura, Sonoko, Ito, Masamichi, Naito, Atsuhiko T., Harada, Mutsuo, Toko, Haruhiro, Nomura, Seitaro, Kumagai, Hidetoshi, Ikeda, Yuichi, Ueno, Hiroo, Takimoto, Eiki, Akazawa, Hiroshi, Morita, Hiroyuki, Aburatani, Hiroyuki, Hata, Yutaka, Uchiyama, Masanobu, Komuro, Issei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
PRECLINICAL RESEARCH
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234526/
https://www.ncbi.nlm.nih.gov/pubmed/30456335
http://dx.doi.org/10.1016/j.jacbts.2018.07.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234526/
https://www.ncbi.nlm.nih.gov/pubmed/30456335
http://dx.doi.org/10.1016/j.jacbts.2018.07.005

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