HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury

BACKGROUND: In muscular dystrophy and old age, skeletal muscle repair is compromised leading to fibrosis and fatty tissue accumulation. Therefore, therapies that protect skeletal muscle or enhance repair would be valuable medical treatments. Hypoxia-inducible factors (HIFs) regulate gene transcripti...

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Detalles Bibliográficos
Autores principales: Billin, Andrew N., Honeycutt, Samuel E., McDougal, Alan V., Kerr, Jaclyn P., Chen, Zhe, Freudenberg, Johannes M., Rajpal, Deepak K., Luo, Guizhen, Kramer, Henning Fritz, Geske, Robert S., Fang, Frank, Yao, Bert, Clark, Richard V., Lepore, John, Cobitz, Alex, Miller, Ram, Nosaka, Kazunori, Hinken, Aaron C., Russell, Alan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234580/
https://www.ncbi.nlm.nih.gov/pubmed/30424786
http://dx.doi.org/10.1186/s13395-018-0179-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234580/
https://www.ncbi.nlm.nih.gov/pubmed/30424786
http://dx.doi.org/10.1186/s13395-018-0179-5

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