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Hypermethylation of the Micro-RNA 145 Promoter Is the Key Regulator for NLRP3 Inflammasome-Induced Activation and Plaque Formation

Two major issues are involved in clinical atherosclerosis treatment. First, there are no significant clinical markers for early diagnosis of atherosclerosis. Second, the plaque will not regress once it initiates even if the risk factors are removed. In this paper, the research shows that the hyperme...

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Detalles Bibliográficos
Autores principales: Zhong, Wei, Li, Bo, Xu, Yao, Yang, Ping, Chen, Rui, Wang, Zhongqun, Shao, Chen, Song, Juan, Yan, Jinchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234615/
https://www.ncbi.nlm.nih.gov/pubmed/30456333
http://dx.doi.org/10.1016/j.jacbts.2018.06.004