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Evaluating the performance of tools used to call minority variants from whole genome short-read data

Background: High-throughput whole genome sequencing facilitates investigation of minority virus sub-populations from virus positive samples. Minority variants are useful in understanding within and between host diversity, population dynamics and can potentially assist in elucidating person-person tr...

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Detalles Bibliográficos
Autores principales: Said Mohammed, Khadija, Kibinge, Nelson, Prins, Pjotr, Agoti, Charles N., Cotten, Matthew, Nokes, D.J., Brand, Samuel, Githinji, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234735/
https://www.ncbi.nlm.nih.gov/pubmed/30483597
http://dx.doi.org/10.12688/wellcomeopenres.13538.2