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Synergistic Effects of NOTCH/γ-Secretase Inhibition and Standard of Care Treatment Modalities in Non-small Cell Lung Cancer Cells

Background: Lung cancer is the leading cause of cancer death worldwide. More effective treatments are needed to increase durable responses and prolong patient survival. Standard of care treatment for patients with non-operable stage III-IV NSCLC is concurrent chemotherapy and radiation. An activated...

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Detalles Bibliográficos
Autores principales: Sosa Iglesias, Venus, Theys, Jan, Groot, Arjan J., Barbeau, Lydie M. O., Lemmens, Alyssa, Yaromina, Ala, Losen, Mario, Houben, Ruud, Dubois, Ludwig, Vooijs, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234899/
https://www.ncbi.nlm.nih.gov/pubmed/30464927
http://dx.doi.org/10.3389/fonc.2018.00460