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Human Teratoma-Derived Hematopoiesis Is a Highly Polyclonal Process Supported by Human Umbilical Vein Endothelial Cells

Hematopoietic stem cells (HSCs) ensure a life-long regeneration of the blood system and are therefore an important source for transplantation and gene therapy. The teratoma environment supports the complex development of functional HSCs from human pluripotent stem cells, which is difficult to recapi...

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Detalles Bibliográficos
Autores principales: Philipp, Friederike, Selich, Anton, Rothe, Michael, Hoffmann, Dirk, Rittinghausen, Susanne, Morgan, Michael A., Klatt, Denise, Glage, Silke, Lienenklaus, Stefan, Neuhaus, Vanessa, Sewald, Katherina, Braun, Armin, Schambach, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234902/
https://www.ncbi.nlm.nih.gov/pubmed/30344010
http://dx.doi.org/10.1016/j.stemcr.2018.09.010