Mitochondrial Dysregulation and Impaired Autophagy in iPSC-Derived Dopaminergic Neurons of Multiple System Atrophy

Multiple system atrophy (MSA) is a progressive neurodegenerative disease that affects several areas of the CNS, whose pathogenesis is still widely unclear and for which an effective treatment is lacking. We have generated induced pluripotent stem cell-derived dopaminergic neurons from four MSA patie...

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Detalles Bibliográficos
Autores principales: Monzio Compagnoni, Giacomo, Kleiner, Giulio, Samarani, Maura, Aureli, Massimo, Faustini, Gaia, Bellucci, Arianna, Ronchi, Dario, Bordoni, Andreina, Garbellini, Manuela, Salani, Sabrina, Fortunato, Francesco, Frattini, Emanuele, Abati, Elena, Bergamini, Christian, Fato, Romana, Tabano, Silvia, Miozzo, Monica, Serratto, Giulia, Passafaro, Maria, Deleidi, Michela, Silipigni, Rosamaria, Nizzardo, Monica, Bresolin, Nereo, Comi, Giacomo P., Corti, Stefania, Quinzii, Catarina M., Di Fonzo, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234905/
https://www.ncbi.nlm.nih.gov/pubmed/30344007
http://dx.doi.org/10.1016/j.stemcr.2018.09.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234905/
https://www.ncbi.nlm.nih.gov/pubmed/30344007
http://dx.doi.org/10.1016/j.stemcr.2018.09.007

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