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Early Human Hemogenic Endothelium Generates Primitive and Definitive Hematopoiesis In Vitro

The differentiation of human embryonic stem cells (hESCs) to hematopoietic lineages initiates with the specification of hemogenic endothelium, a transient specialized endothelial precursor of all blood cells. This in vitro system provides an invaluable model to dissect the emergence of hematopoiesis...

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Detalles Bibliográficos
Autores principales: Garcia-Alegria, Eva, Menegatti, Sara, Fadlullah, Muhammad Z.H., Menendez, Pablo, Lacaud, Georges, Kouskoff, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234921/
https://www.ncbi.nlm.nih.gov/pubmed/30449319
http://dx.doi.org/10.1016/j.stemcr.2018.09.013