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Connexin 30 Deficiency Attenuates Chronic but Not Acute Phases of Experimental Autoimmune Encephalomyelitis Through Induction of Neuroprotective Microglia

Glial connexins (Cxs) form gap junction channels through which a pan-glial network plays key roles in maintaining homeostasis of the central nervous system (CNS). In multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), expression of astrocytic Cx43 is lost i...

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Detalles Bibliográficos
Autores principales: Fang, Mei, Yamasaki, Ryo, Li, Guangrui, Masaki, Katsuhisa, Yamaguchi, Hiroo, Fujita, Atsushi, Isobe, Noriko, Kira, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234958/
https://www.ncbi.nlm.nih.gov/pubmed/30464764
http://dx.doi.org/10.3389/fimmu.2018.02588