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Tumor-suppressive function of SIRT4 in neuroblastoma through mitochondrial damage
BACKGROUND: SIRT4 is a member of the sirtuin family of nicotinamide adenine dinucleotide-dependent enzymes located in the mitochondria, and is involved in regulating energy metabolism, stress response, and cellular lifespan in mammalian cells. However, its function in human neuroblastoma (NB) remain...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234993/ https://www.ncbi.nlm.nih.gov/pubmed/30519106 http://dx.doi.org/10.2147/CMAR.S172509 |