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Tumor-suppressive function of SIRT4 in neuroblastoma through mitochondrial damage

BACKGROUND: SIRT4 is a member of the sirtuin family of nicotinamide adenine dinucleotide-dependent enzymes located in the mitochondria, and is involved in regulating energy metabolism, stress response, and cellular lifespan in mammalian cells. However, its function in human neuroblastoma (NB) remain...

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Detalles Bibliográficos
Autores principales:	Wang, Yumei, Guo, Yinmou, Gao, Jianzhi, Yuan, Xiangdong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234993/ https://www.ncbi.nlm.nih.gov/pubmed/30519106 http://dx.doi.org/10.2147/CMAR.S172509

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