Gene expression of hENT1, dCK, CDA, dCMPD and topoisomerase IIα as an indicator of chemotherapy response in AML treated with cytarabine and daunorubicin

PURPOSE: Acute myeloid leukemia patients are commonly treated with cytarabine (Ara-C) and anthracyclines but the sustained remission rate is not very promising. We explored the role of drug-metabolizing enzymes and transporters in the therapeutic response. PATIENTS AND METHODS: Bone marrow and perip...

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Detalles Bibliográficos
Autores principales: Kulsoom, Bibi, Shamsi, Tahir Sultan, Afsar, Nasir Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235003/
https://www.ncbi.nlm.nih.gov/pubmed/30519105
http://dx.doi.org/10.2147/CMAR.S181299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235003/
https://www.ncbi.nlm.nih.gov/pubmed/30519105
http://dx.doi.org/10.2147/CMAR.S181299

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