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miRNA expression profiles in Smad4-positive and Smad4-negative SW620 human colon cancer cells detected by next-generation small RNA sequencing

BACKGROUND AND AIMS: SMAD4, as a tumor suppressive gene in human colon cancer, inhibits the metastasis of colon adenocarcinoma cells. However, the molecular mechanisms are unclear. miRNAs play an important role in the pathogenesis and progression of cancer. METHODS: In this study, a deep sequencing...

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Detalles Bibliográficos
Autores principales: Yan, Wei, Liu, Zhongcai, Yang, Wenchao, Wu, Guoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235008/
https://www.ncbi.nlm.nih.gov/pubmed/30519096
http://dx.doi.org/10.2147/CMAR.S178261