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Prognostic significance of tumor genotypes and CD8+ infiltrates in stage I-III colorectal cancer

BACKGROUND: We explored the clinical significance of tumor genotypes and immunophenotypes in non-metastatic colorectal cancer (CRC). METHODS: In primary tumors (paraffin blocks) from 412 CRC patients treated with adjuvant chemotherapy, we examined pathogenic mutations (panel NGS; 347 informative); m...

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Detalles Bibliográficos
Autores principales: Fountzilas, Elena, Kotoula, Vassiliki, Tikas, Ioannis, Manousou, Kyriaki, Papadopoulou, Kyriaki, Poulios, Christos, Karavasilis, Vasilios, Efstratiou, Ioannis, Pectasides, Dimitrios, Papaparaskeva, Kleo, Varthalitis, Ioannis, Christodoulou, Christos, Papatsibas, George, Chrisafi, Sofia, Glantzounis, Georgios K., Psyrri, Amanda, Aravantinos, Gerasimos, Koliou, Georgia-Angeliki, Koukoulis, George K., Pentheroudakis, George E., Fountzilas, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235022/
https://www.ncbi.nlm.nih.gov/pubmed/30479693
http://dx.doi.org/10.18632/oncotarget.26256