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29-kDa FN-f inhibited autophagy through modulating localization of HMGB1 in human articular chondrocytes

Fibronectin fragments found in the synovial fluid of patients with osteoarthritis (OA) induce the catabolic responses in cartilage. Nuclear high-mobility group protein Box 1 (HMGB1), a damage-associated molecular pattern, is responsible for the regulation of signaling pathways related to cell death...

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Detalles Bibliográficos
Autores principales: Hwang, Hyun Sook, Choi, Min Ha, Kim, Hyun Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235092/
https://www.ncbi.nlm.nih.gov/pubmed/29804557
http://dx.doi.org/10.5483/BMBRep.2018.51.10.058