Cargando…

Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay

The administration of enzyme replacement therapies (ERTs) and other biologic therapies to patients may elicit an anti-drug immune response. The characterization of these anti-drug antibodies (ADA), especially those that may neutralize the biological activity of the drug, termed neutralizing antibodi...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheung, Ruby, deHart, Gregory W., Jesaitis, Lynne, Zoog, Stephen J., Melton, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235114/
https://www.ncbi.nlm.nih.gov/pubmed/30247460
http://dx.doi.org/10.3791/57777