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Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay
The administration of enzyme replacement therapies (ERTs) and other biologic therapies to patients may elicit an anti-drug immune response. The characterization of these anti-drug antibodies (ADA), especially those that may neutralize the biological activity of the drug, termed neutralizing antibodi...
Autores principales: | Cheung, Ruby, deHart, Gregory W., Jesaitis, Lynne, Zoog, Stephen J., Melton, Andrew C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MyJove Corporation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235114/ https://www.ncbi.nlm.nih.gov/pubmed/30247460 http://dx.doi.org/10.3791/57777 |
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