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B Cell Competition for Restricted T Cell Help Suppresses Rare-Epitope Responses
The immune system responds preferentially to particular antigenic-epitopes contained within complex immunogens, such as proteins or microbes. This poorly understood phenomenon, termed ‘‘immunodominance,’’ remains an obstacle to achieving polyvalent immune responses against multiple anti-genic-epitop...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235168/ https://www.ncbi.nlm.nih.gov/pubmed/30304673 http://dx.doi.org/10.1016/j.celrep.2018.09.029 |