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B Cell Competition for Restricted T Cell Help Suppresses Rare-Epitope Responses

The immune system responds preferentially to particular antigenic-epitopes contained within complex immunogens, such as proteins or microbes. This poorly understood phenomenon, termed ‘‘immunodominance,’’ remains an obstacle to achieving polyvalent immune responses against multiple anti-genic-epitop...

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Detalles Bibliográficos
Autores principales:	Woodruff, Matthew Charles, Kim, Eui Ho, Luo, Wei, Pulendran, Bali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235168/ https://www.ncbi.nlm.nih.gov/pubmed/30304673 http://dx.doi.org/10.1016/j.celrep.2018.09.029

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