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Downregulation of miRNA17–92 cluster marks Vγ9Vδ2 T cells from patients with rheumatoid arthritis

BACKGROUND: We aimed to evaluate the phenotype, function, and microRNA (miRNA)17–92 cluster expression in Vγ9Vδ2 T-cell subsets and the correlation with immune response in rheumatoid arthritis (RA) patients. METHODS: Peripheral blood from 10 early RA untreated patients and 10 healthy donors (HD) was...

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Detalles Bibliográficos
Autores principales: Guggino, Giuliana, Orlando, Valentina, Saieva, Laura, Ruscitti, Piero, Cipriani, Paola, La Manna, Marco Pio, Giacomelli, Roberto, Alessandro, Riccardo, Triolo, Giovanni, Ciccia, Francesco, Dieli, Francesco, Caccamo, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235230/
https://www.ncbi.nlm.nih.gov/pubmed/30348222
http://dx.doi.org/10.1186/s13075-018-1740-7