IL-2Rα up-regulation is mediated by latent membrane protein 1 and promotes lymphomagenesis and chemotherapy resistance in natural killer/T-cell lymphoma

BACKGROUND: Natural killer/T-cell lymphoma (NKTCL) is a highly aggressive non-Hodgkin lymphoma often resistant to chemotherapy. Serum level of soluble IL-2 receptor α (IL-2Rα) is elevated in NKTCL patients and correlates significantly with treatment response and survival. In the current study we exa...

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Detalles Bibliográficos
Autores principales: Wang, Liang, Bi, Xi-wen, Zhu, Yu-jia, He, Ying-zhi, Lai, Qiu-yu, Xia, Zhong-jun, Cai, Qing-qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235395/
https://www.ncbi.nlm.nih.gov/pubmed/30340635
http://dx.doi.org/10.1186/s40880-018-0334-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235395/
https://www.ncbi.nlm.nih.gov/pubmed/30340635
http://dx.doi.org/10.1186/s40880-018-0334-8

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