Ultra-rapid near universal TB drug regimen identified via parabolic response surface platform cures mice of both conventional and high susceptibility

As current treatment of tuberculosis is burdensomely long, provoking non-adherence and drug resistance, effective short-course treatments are needed. Using the output-driven parabolic response surface (PRS) platform, we have identified drug regimens that treat tuberculosis more rapidly in mice than...

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Detalles Bibliográficos
Autores principales: Lee, Bai-Yu, Clemens, Daniel L., Silva, Aleidy, Dillon, Barbara Jane, Masleša-Galić, Saša, Nava, Susana, Ho, Chih-Ming, Horwitz, Marcus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235396/
https://www.ncbi.nlm.nih.gov/pubmed/30427938
http://dx.doi.org/10.1371/journal.pone.0207469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235396/
https://www.ncbi.nlm.nih.gov/pubmed/30427938
http://dx.doi.org/10.1371/journal.pone.0207469

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