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Ultra-rapid near universal TB drug regimen identified via parabolic response surface platform cures mice of both conventional and high susceptibility
As current treatment of tuberculosis is burdensomely long, provoking non-adherence and drug resistance, effective short-course treatments are needed. Using the output-driven parabolic response surface (PRS) platform, we have identified drug regimens that treat tuberculosis more rapidly in mice than...
Autores principales: | Lee, Bai-Yu, Clemens, Daniel L., Silva, Aleidy, Dillon, Barbara Jane, Masleša-Galić, Saša, Nava, Susana, Ho, Chih-Ming, Horwitz, Marcus A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235396/ https://www.ncbi.nlm.nih.gov/pubmed/30427938 http://dx.doi.org/10.1371/journal.pone.0207469 |
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