Unveiling the structural features that determine the dual methyltransferase activities of Streptococcus pneumoniae RlmCD

Methyltransferase RlmCD was previously shown to be responsible for the introduction of C5 methylation at both U747 and U1939 of the 23S ribosomal RNA in Streptococcus pneumoniae. Intriguingly, its structural homologue, RumA, can only catalyze the methylation of U1939, while RlmC is the dedicated enz...

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Detalles Bibliográficos
Autores principales: Jiang, Yiyang, Yu, Hailong, Li, Fudong, Cheng, Lin, Zhu, Lingru, Shi, Yunyu, Gong, Qingguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235398/
https://www.ncbi.nlm.nih.gov/pubmed/30388185
http://dx.doi.org/10.1371/journal.ppat.1007379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235398/
https://www.ncbi.nlm.nih.gov/pubmed/30388185
http://dx.doi.org/10.1371/journal.ppat.1007379

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