Cargando…

Unveiling the structural features that determine the dual methyltransferase activities of Streptococcus pneumoniae RlmCD

Methyltransferase RlmCD was previously shown to be responsible for the introduction of C5 methylation at both U747 and U1939 of the 23S ribosomal RNA in Streptococcus pneumoniae. Intriguingly, its structural homologue, RumA, can only catalyze the methylation of U1939, while RlmC is the dedicated enz...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Yiyang, Yu, Hailong, Li, Fudong, Cheng, Lin, Zhu, Lingru, Shi, Yunyu, Gong, Qingguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235398/ https://www.ncbi.nlm.nih.gov/pubmed/30388185 http://dx.doi.org/10.1371/journal.ppat.1007379

Ejemplares similares

Structural insights into substrate selectivity of ribosomal RNA methyltransferase RlmCD
por: Jiang, Yiyang, et al.
Publicado: (2017)

RlmCD-mediated U747 methylation promotes efficient G748 methylation by methyltransferase RlmA(II) in 23S rRNA in Streptococcus pneumoniae; interplay between two rRNA methylations responsible for telithromycin susceptibility
por: Shoji, Tatsuma, et al.
Publicado: (2015)

A single methyltransferase YefA (RlmCD) catalyses both m(5)U747 and m(5)U1939 modifications in Bacillus subtilis 23S rRNA
por: Desmolaize, Benoit, et al.
Publicado: (2011)

Biochemical and Computational Analysis of the Substrate Specificities of Cfr and RlmN Methyltransferases
por: Ntokou, Eleni, et al.
Publicado: (2015)

Structural insights into a unique preference for 3′ terminal guanine of mirtron in Drosophila TUTase tailor
por: Cheng, Lin, et al.
Publicado: (2019)

Brassica napus genes Rlm4 and Rlm7, conferring resistance to Leptosphaeria maculans, are alleles of the Rlm9 wall‐associated kinase‐like resistance locus
por: Haddadi, Parham, et al.
Publicado: (2022)

Structural and functional insights into the molecular mechanism of rRNA m6A methyltransferase RlmJ
por: Punekar, Avinash S., et al.
Publicado: (2013)

Small methyltransferase RlmH assembles a composite active site to methylate a ribosomal pseudouridine
por: Koh, Cha San, et al.
Publicado: (2017)

Crystal structure of RlmM, the 2′O-ribose methyltransferase for C2498 of Escherichia coli 23S rRNA
por: Punekar, Avinash S., et al.
Publicado: (2012)

Purification, crystallization and preliminary X-ray diffraction analysis of the 23S rRNA methyltransferase RlmJ from Escherichia coli
por: Punekar, Avinash S., et al.
Publicado: (2013)

Crystal structure of tRNA m(1)G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate
por: Shao, Zhenhua, et al.
Publicado: (2014)

Determinants of tRNA Recognition by the Radical SAM Enzyme RlmN
por: Fitzsimmons, Christina M., et al.
Publicado: (2016)

Unveiling an indole alkaloid diketopiperazine biosynthetic pathway that features a unique stereoisomerase and multifunctional methyltransferase
por: Deletti, Garrett, et al.
Publicado: (2023)

Molecular mechanism underlying the di-uridylation activity of Arabidopsis TUTase URT1
por: Hu, Qian, et al.
Publicado: (2022)

The Role of Candida albicans Transcription Factor RLM1 in Response to Carbon Adaptation
por: Oliveira-Pacheco, João, et al.
Publicado: (2018)

Structure of the bifunctional methyltransferase YcbY (RlmKL) that adds the m(7)G2069 and m(2)G2445 modifications in Escherichia coli 23S rRNA
por: Wang, Kai-Tuo, et al.
Publicado: (2012)

Structural insights into the recognition of the internal A-rich linker from OxyS sRNA by Escherichia coli Hfq
por: Wang, Lijun, et al.
Publicado: (2015)

Participation of Candida albicans Transcription Factor RLM1 in Cell Wall Biogenesis and Virulence
por: Delgado-Silva, Yolanda, et al.
Publicado: (2014)

Crystal Structure of Arginine Methyltransferase 6 from Trypanosoma brucei
por: Wang, Chongyuan, et al.
Publicado: (2014)

The Bacillus subtilis open reading frame ysgA encodes the SPOUT methyltransferase RlmP forming 2′-O-methylguanosine at position 2553 in the A-loop of 23S rRNA
por: Roovers, Martine, et al.
Publicado: (2022)

Independent breakdown events of the Brassica napus Rlm7 resistance gene including via the off‐target impact of a dual‐specificity avirulence interaction
por: Van de Wouw, Angela P., et al.
Publicado: (2022)

Genome-wide transcriptome reveals mechanisms underlying Rlm1-mediated blackleg resistance on canola
por: Zhai, Chun, et al.
Publicado: (2021)

RLM: fast and simplified extraction of read-level methylation metrics from bisulfite sequencing data
por: Hetzel, Sara, et al.
Publicado: (2021)

Structural insights into the recognition of phosphorylated FUNDC1 by LC3B in mitophagy
por: Lv, Mengqi, et al.
Publicado: (2016)

Characterization of a Cross-Linked Protein–Nucleic Acid Substrate Radical in the Reaction Catalyzed by RlmN
por: Silakov, Alexey, et al.
Publicado: (2014)

Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases
por: Kanwal, Rajnee, et al.
Publicado: (2016)

Aspergillus fumigatus MADS-Box Transcription Factor rlmA Is Required for Regulation of the Cell Wall Integrity and Virulence
por: Rocha, Marina Campos, et al.
Publicado: (2016)

Fine mapping of Brassica napus blackleg resistance gene Rlm1 through bulked segregant RNA sequencing
por: Fu, Fuyou, et al.
Publicado: (2019)

Dissection of Quantitative Blackleg Resistance Reveals Novel Variants of Resistance Gene Rlm9 in Elite Brassica napus
por: Vollrath, Paul, et al.
Publicado: (2021)

Correction: Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases
por: Kanwal, Rajnee, et al.
Publicado: (2016)

Structural and biochemical insights into human zinc finger protein AEBP2 reveals interactions with RBBP4
por: Sun, Aiai, et al.
Publicado: (2017)

Discovery of prenylated flavonoids with dual activity against influenza virus and Streptococcus pneumoniae
por: Grienke, Ulrike, et al.
Publicado: (2016)

Structural and functional characterization of hMEX‐3C Ring finger domain as an E3 ubiquitin ligase
por: Moududee, Sayed Ala, et al.
Publicado: (2018)

Pneumonia and Streptococcus pneumoniae vaccine
por: Kim, Gyu-Lee, et al.
Publicado: (2017)

Re-evaluation of Streptococcus pneumoniae carriage in Portuguese elderly by qPCR increases carriage estimates and unveils an expanded pool of serotypes
por: Almeida, Sónia T., et al.
Publicado: (2020)

Co-localisation of the blackleg resistance genes Rlm2 and LepR3 on Brassica napus chromosome A10
por: Larkan, Nicholas J, et al.
Publicado: (2014)

Elp3 and RlmN: A tale of two mitochondrial tail-anchored radical SAM enzymes in Toxoplasma gondii
por: Padgett, Leah R., et al.
Publicado: (2018)

Effectiveness of Rlm7 resistance against Leptosphaeria maculans (phoma stem canker) in UK winter oilseed rape cultivars
por: Mitrousia, G. K., et al.
Publicado: (2018)

MADS-Box Transcription Factor ZtRlm1 Is Responsible for Virulence and Development of the Fungal Wheat Pathogen Zymoseptoria tritici
por: Mohammadi, Naser, et al.
Publicado: (2020)

An expanded cell wall damage signaling network is comprised of the transcription factors Rlm1 and Sko1 in Candida albicans
por: Heredia, Marienela Y., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_c8432g1viivdsq0s89mtp0nick