Autocrine-based selection of ligands for personalized CAR-T therapy of lymphoma

We report the development of a novel platform to enhance the efficacy and safety of follicular lymphoma (FL) treatment. Since lymphoma is a clonal malignancy of a diversity system, every tumor has a different antibody on its cell surface. Combinatorial autocrine-based selection is used to rapidly id...

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Detalles Bibliográficos
Autores principales: Stepanov, Alexey V., Markov, Oleg V., Chernikov, Ivan V., Gladkikh, Daniil V., Zhang, Hongkai, Jones, Teresa, Sen’kova, Alexandra V., Chernolovskaya, Elena L., Zenkova, Marina A., Kalinin, Roman S., Rubtsova, Maria P., Meleshko, Alexander N., Genkin, Dmitry D., Belogurov, Alexey A., Xie, Jia, Gabibov, Alexander G., Lerner, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235538/
https://www.ncbi.nlm.nih.gov/pubmed/30443597
http://dx.doi.org/10.1126/sciadv.aau4580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235538/
https://www.ncbi.nlm.nih.gov/pubmed/30443597
http://dx.doi.org/10.1126/sciadv.aau4580

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