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OSCA/TMEM63 are an evolutionarily conserved family of mechanically activated ion channels

Mechanically activated (MA) ion channels convert physical forces into electrical signals, and are essential for eukaryotic physiology. Despite their importance, few bona-fide MA channels have been described in plants and animals. Here, we show that various members of the OSCA and TMEM63 family of pr...

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Detalles Bibliográficos
Autores principales: Murthy, Swetha E, Dubin, Adrienne E, Whitwam, Tess, Jojoa-Cruz, Sebastian, Cahalan, Stuart M, Mousavi, Seyed Ali Reza, Ward, Andrew B, Patapoutian, Ardem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235560/
https://www.ncbi.nlm.nih.gov/pubmed/30382938
http://dx.doi.org/10.7554/eLife.41844