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High-throughput Measurement of Gut Transit Time Using Larval Zebrafish

Zebrafish are used as alternative model organisms for drug safety testing. The gastrointestinal (GI) tract of zebrafish has genetic, neuronal, and pharmacological similarities to that of the mammals. GI intolerance during clinical testing of drug candidates is common and may pose a serious threat to...

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Detalles Bibliográficos
Autores principales: Cassar, Steven, Huang, Xin, Cole, Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235591/
https://www.ncbi.nlm.nih.gov/pubmed/30417875
http://dx.doi.org/10.3791/58497