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High-throughput Measurement of Gut Transit Time Using Larval Zebrafish
Zebrafish are used as alternative model organisms for drug safety testing. The gastrointestinal (GI) tract of zebrafish has genetic, neuronal, and pharmacological similarities to that of the mammals. GI intolerance during clinical testing of drug candidates is common and may pose a serious threat to...
Autores principales: | Cassar, Steven, Huang, Xin, Cole, Todd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MyJove Corporation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235591/ https://www.ncbi.nlm.nih.gov/pubmed/30417875 http://dx.doi.org/10.3791/58497 |
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