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Selective Elimination of Culture-Adapted Human Embryonic Stem Cells with BH3 Mimetics
The selective survival advantage of culture-adapted human embryonic stem cells (hESCs) is a serious safety concern for their clinical application. With a set of hESCs with various passage numbers, we observed that a subpopulation of hESCs at late passage numbers was highly resistant to various cell...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235677/ https://www.ncbi.nlm.nih.gov/pubmed/30293852 http://dx.doi.org/10.1016/j.stemcr.2018.09.002 |