IFNL4-ΔG is associated with prostate cancer among men at increased risk of sexually transmitted infections

Sexually transmitted infections can reach the prostate gland where their harmful effects are mediated by innate immunity, including interferons. Humans are polymorphic for the germline dinucleotide variant, rs368234815-TT/ΔG, in the IFNL4 gene encoding interferon λ4. Since the IFNL4-ΔG allele has be...

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Detalles Bibliográficos
Autores principales: Minas, Tsion Zewdu, Tang, Wei, Smith, Cheryl J., Onabajo, Olusegun O., Obajemu, Adeola, Dorsey, Tiffany H., Jordan, Symone V., Obadi, Obadi M., Ryan, Bríd M., Prokunina-Olsson, Ludmila, Loffredo, Christopher A., Ambs, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235841/
https://www.ncbi.nlm.nih.gov/pubmed/30456312
http://dx.doi.org/10.1038/s42003-018-0193-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235841/
https://www.ncbi.nlm.nih.gov/pubmed/30456312
http://dx.doi.org/10.1038/s42003-018-0193-5

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