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Trapping intermediates in metal transfer reactions of the CusCBAF export pump of Escherichia coli

Escherichia coli CusCBAF represents an important class of bacterial efflux pump exhibiting selectivity towards Cu(I) and Ag(I). The complex is comprised of three proteins: the CusA transmembrane pump, the CusB soluble adaptor protein, and the CusC outer-membrane pore, and additionally requires the p...

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Detalles Bibliográficos
Autores principales: Chacón, Kelly N., Perkins, Jonathan, Mathe, Zachary, Alwan, Katherine, Ho, Ethan N., Ucisik, Melek N., Merz, Kenneth M., Blackburn, Ninian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235853/
https://www.ncbi.nlm.nih.gov/pubmed/30456313
http://dx.doi.org/10.1038/s42003-018-0181-9