Mettl3-mediated m(6)A RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis

N(6)-methyladenosine (m(6)A) is the most abundant epigenetic modification in eukaryotic mRNAs and is essential for multiple RNA processing events during mammalian development and disease control. Here we show that conditional knockout of the m(6)A methyltransferase Mettl3 in bone marrow mesenchymal...

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Detalles Bibliográficos
Autores principales: Wu, Yunshu, Xie, Liang, Wang, Mengyuan, Xiong, Qiuchan, Guo, Yuchen, Liang, Yu, Li, Jing, Sheng, Rui, Deng, Peng, Wang, Yuan, Zheng, Rixin, Jiang, Yizhou, Ye, Ling, Chen, Qianming, Zhou, Xuedong, Lin, Shuibin, Yuan, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235890/
https://www.ncbi.nlm.nih.gov/pubmed/30429466
http://dx.doi.org/10.1038/s41467-018-06898-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235890/
https://www.ncbi.nlm.nih.gov/pubmed/30429466
http://dx.doi.org/10.1038/s41467-018-06898-4

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