Glucocorticoid-mediated ER-mitochondria contacts reduce AMPA receptor and mitochondria trafficking into cell terminus via microtubule destabilization

Glucocorticoid, a major risk factor of Alzheimer’s disease (AD), is widely known to promote microtubule dysfunction recognized as the early pathological feature that culminates in memory deficits. However, the exact glucocorticoid receptor (GR)-mediated mechanism of how glucocorticoid triggers micro...

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Detalles Bibliográficos
Autores principales: Choi, Gee Euhn, Oh, Ji Young, Lee, Hyun Jik, Chae, Chang Woo, Kim, Jun Sung, Jung, Young Hyun, Han, Ho Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235892/
https://www.ncbi.nlm.nih.gov/pubmed/30429451
http://dx.doi.org/10.1038/s41419-018-1172-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235892/
https://www.ncbi.nlm.nih.gov/pubmed/30429451
http://dx.doi.org/10.1038/s41419-018-1172-y

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