Making CAR T Cells a Solid Option for Solid Tumors

Adoptive cell therapy with chimeric antigen receptor (CAR) T cells aims to redirect the patient's own immune system to selectively attack cancer cells. To do so, CAR T cells are endowed with specific antigen recognition moieties fused to signaling and costimulatory domains. While this approach...

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Detalles Bibliográficos
Autores principales: Schmidts, Andrea, Maus, Marcela V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235951/
https://www.ncbi.nlm.nih.gov/pubmed/30467505
http://dx.doi.org/10.3389/fimmu.2018.02593