Millisecond Timescale Motions Connect Amino Acid Interaction Networks in Alpha Tryptophan Synthase

Tryptophan synthase is a model system for understanding allosteric regulation within enzyme complexes. Amino acid interaction networks were previously delineated in the isolated alpha subunit (αTS) in the absence of the beta subunit (βTS). The amino acid interaction networks were different between t...

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Detalles Bibliográficos
Autores principales: O'Rourke, Kathleen F., Axe, Jennifer M., D'Amico, Rebecca N., Sahu, Debashish, Boehr, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236060/
https://www.ncbi.nlm.nih.gov/pubmed/30467546
http://dx.doi.org/10.3389/fmolb.2018.00092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236060/
https://www.ncbi.nlm.nih.gov/pubmed/30467546
http://dx.doi.org/10.3389/fmolb.2018.00092

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