Spatial learning and long‐term memory impairments in RasGrf1 KO, Pttg1 KO, and double KO mice

BACKGROUND: RasGrf1 is a guanine‐nucleotide releasing factor that enhances Ras activity. Human PTTG1 is an oncoprotein found in pituitary tumors and later identified as securin, a protein isolated from yeast with a reported role in chromosome separation. It has been suggested that RasGrf1 is an impo...

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Detalles Bibliográficos
Autores principales: Manyes, Lara, Holst, Sarah, Lozano, Manuel, Santos, Eugenio, Fernandez‐Medarde, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236249/
https://www.ncbi.nlm.nih.gov/pubmed/30259712
http://dx.doi.org/10.1002/brb3.1089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236249/
https://www.ncbi.nlm.nih.gov/pubmed/30259712
http://dx.doi.org/10.1002/brb3.1089

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