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Spatial learning and long‐term memory impairments in RasGrf1 KO, Pttg1 KO, and double KO mice
BACKGROUND: RasGrf1 is a guanine‐nucleotide releasing factor that enhances Ras activity. Human PTTG1 is an oncoprotein found in pituitary tumors and later identified as securin, a protein isolated from yeast with a reported role in chromosome separation. It has been suggested that RasGrf1 is an impo...
Autores principales: | Manyes, Lara, Holst, Sarah, Lozano, Manuel, Santos, Eugenio, Fernandez‐Medarde, Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236249/ https://www.ncbi.nlm.nih.gov/pubmed/30259712 http://dx.doi.org/10.1002/brb3.1089 |
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