Andrographolide mitigates IL-1β-induced human nucleus pulposus cells degeneration through the TLR4/MyD88/NF-κB signaling pathway

Intervertebral disc degeneration (IDD) is a multifactorial disease with few efficacious clinical drugs, which has been demonstrated to be associated with nucleus pulposus (NP) cells apoptosis and degeneration of the extracellular matrix (ECM). Interleukin (IL)-1β, a common proinflammatory cytokine,...

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Detalles Bibliográficos
Autores principales: Zhang, Lilian, Chen, Qi, Wang, Haoli, Yang, Jian, Sheng, Sunren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236278/
https://www.ncbi.nlm.nih.gov/pubmed/30365119
http://dx.doi.org/10.3892/mmr.2018.9599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236278/
https://www.ncbi.nlm.nih.gov/pubmed/30365119
http://dx.doi.org/10.3892/mmr.2018.9599

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