Ketamine destabilizes growth of dendritic spines in developing hippocampal neurons in vitro via a Rho-dependent mechanism

The safety of anesthetics on the developing brain has caused concern. Ketamine, an N-methyl-D-aspartate receptor antagonist, is widely used as a general pediatric anesthetic. Recent studies suggested that ketamine alters the plasticity of dendritic spines in the developing brain and may be an import...

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Detalles Bibliográficos
Autores principales: Jiang, Sufang, Hao, Zimiao, Li, Xuze, Bo, Lijun, Zhang, Rui, Wang, Ying, Duan, Xiaofeng, Kang, Rongtian, Huang, Lining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236282/
https://www.ncbi.nlm.nih.gov/pubmed/30280188
http://dx.doi.org/10.3892/mmr.2018.9531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236282/
https://www.ncbi.nlm.nih.gov/pubmed/30280188
http://dx.doi.org/10.3892/mmr.2018.9531

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