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Ketamine destabilizes growth of dendritic spines in developing hippocampal neurons in vitro via a Rho-dependent mechanism
The safety of anesthetics on the developing brain has caused concern. Ketamine, an N-methyl-D-aspartate receptor antagonist, is widely used as a general pediatric anesthetic. Recent studies suggested that ketamine alters the plasticity of dendritic spines in the developing brain and may be an import...
Autores principales: | Jiang, Sufang, Hao, Zimiao, Li, Xuze, Bo, Lijun, Zhang, Rui, Wang, Ying, Duan, Xiaofeng, Kang, Rongtian, Huang, Lining |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236282/ https://www.ncbi.nlm.nih.gov/pubmed/30280188 http://dx.doi.org/10.3892/mmr.2018.9531 |
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