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In vitro study of the effects of reprogramming neonatal rat fibroblasts transfected with TBX18 on spontaneous beating in neonatal rat cardiomyocytes

Intracardiac injection of the growth-promoting transcription factor of the sinoatrial node T-box18 (TBX18) has been shown to reprogram cardiomyocytes into induced sinoatrial nodes that produce high-frequency and neuroregulated ectopic beats. Fibroblasts, the most important non-cardiomyocyte cell typ...

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Detalles Bibliográficos
Autores principales: Quan, Dajun, Huang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236286/
https://www.ncbi.nlm.nih.gov/pubmed/30365101
http://dx.doi.org/10.3892/mmr.2018.9566