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In vitro study of the effects of reprogramming neonatal rat fibroblasts transfected with TBX18 on spontaneous beating in neonatal rat cardiomyocytes
Intracardiac injection of the growth-promoting transcription factor of the sinoatrial node T-box18 (TBX18) has been shown to reprogram cardiomyocytes into induced sinoatrial nodes that produce high-frequency and neuroregulated ectopic beats. Fibroblasts, the most important non-cardiomyocyte cell typ...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236286/ https://www.ncbi.nlm.nih.gov/pubmed/30365101 http://dx.doi.org/10.3892/mmr.2018.9566 |