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Mechanism of HN-3 cell apoptosis induced by carboplatin: Combination of mitochondrial pathway associated with Ca(2+) and the nucleus pathways

Laryngeal carcinomas have been recognized as a serious health threat worldwide. In the present study, the mechanism of apoptosis in HN-3 cells induced by carboplatin (CBCDA), a widely used anti-cancer drug, was investigated. The pro-apoptotic effect of CBCDA in HN-3 cells was demonstrated to be time...

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Detalles Bibliográficos
Autores principales: Shen, Bo, Mao, Wenjing, Ahn, Jin-Chul, Chung, Phil-Sang, He, Peijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236313/
https://www.ncbi.nlm.nih.gov/pubmed/30272304
http://dx.doi.org/10.3892/mmr.2018.9507