Use of Cyclic Allylic Bromides in the Zinc–Mediated Aqueous Barbier–Grignard Reaction

The zinc–mediated aqueous Barbier–Grignard reaction of cyclic allylic bromide substrates with various aldehydes and ketones to afford homoallylic alcohols was investigated. Aromatic aldehydes and ketones afforded adducts in good yields (66–90%) and with good diastereoselectivities. Non–aromatic alde...

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Detalles Bibliográficos
Autores principales: Breton, Gary W., Shugart, John H., Hughey, Christine A., Conrad, Brian P., Perala, Suzanne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236354/
http://dx.doi.org/10.3390/60800655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236354/
http://dx.doi.org/10.3390/60800655

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