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Intrathecal Methotrexate-Induced Necrotizing Myelopathy: A Case Report and Review of Histologic Features

Central nervous system (CNS) relapse of acute lymphoblastic leukemia (ALL) is associated with a poor prognosis. However, prophylactic measures, including intrathecal (IT) methotrexate, reduce the incidence of CNS relapse in these patients considerably. Unfortunately, IT methotrexate can cause severa...

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Detalles Bibliográficos
Autores principales: Tariq, Hamza, Gilbert, Andrea, Sharkey, Francis E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236481/
https://www.ncbi.nlm.nih.gov/pubmed/30450009
http://dx.doi.org/10.1177/1179555718809071