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Intrathecal Methotrexate-Induced Necrotizing Myelopathy: A Case Report and Review of Histologic Features
Central nervous system (CNS) relapse of acute lymphoblastic leukemia (ALL) is associated with a poor prognosis. However, prophylactic measures, including intrathecal (IT) methotrexate, reduce the incidence of CNS relapse in these patients considerably. Unfortunately, IT methotrexate can cause severa...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236481/ https://www.ncbi.nlm.nih.gov/pubmed/30450009 http://dx.doi.org/10.1177/1179555718809071 |