An In Vitro Model of Charcot-Marie-Tooth Disease Type 4B2 Provides Insight Into the Roles of MTMR13 and MTMR2 in Schwann Cell Myelination

Charcot-Marie-Tooth Disorder Type 4B (CMT4B) is a demyelinating peripheral neuropathy caused by mutations in myotubularin-related (MTMR) proteins 2, 13, or 5 (CMT4B1/2/3), which regulate phosphoinositide turnover and endosomal trafficking. Although mouse models of CMT4B2 exist, an in vitro model wou...

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Detalles Bibliográficos
Autores principales: Robinson, Danielle C., Mammel, Anna E., Logan, Anne M., Larson, Aubree A., Schmidt, Eric J., Condon, Alec F., Robinson, Fred L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236487/
https://www.ncbi.nlm.nih.gov/pubmed/30419760
http://dx.doi.org/10.1177/1759091418803282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236487/
https://www.ncbi.nlm.nih.gov/pubmed/30419760
http://dx.doi.org/10.1177/1759091418803282

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